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ALT Analysis

Alanine Transaminase analysis (ALT) is one of the many laboratory services TGA Sciences provides to the Pharmaceutical, Biotechnology and Academic.

ALT is widely distributed in many tissues but is found in greatest abundance in the liver, and to a much lesser extent in the kidneys, heart, and brain. ALT has also been found to play an important role in neuronal function by supplying an important source of neuronal glutamate through the analine-aminotransferase reaction. Serum ALT levels are generally low, but may spike during disease states or in the event of tissue injury and are routinely used as indicators of medical issues, particularly liver diseases. Increased levels can be seen in patients with diabetes, cirrhosis, fatty liver disease, and hepatitis. Beyond liver disease, increased ALT levels have been noted in cases of carcinoma, mononucleosis, muscular dystrophy, and cardiovascular disease.

About TGA Sciences

TGA Sciences, Inc. is a contract research organization (CRO) that provides its Pharmaceutical, Biotechnology and Academic clients a comprehensive range of laboratory services in support of basic research and development as well as for clinical studies. We offer a complete package of customized testing systems utilized in pre-clinical through Phase IV studies, including custom assay development, in vivo animal studies,cell-based assays, various immunological-based testing, as well as sample storage. We serve clients both in the U.S. and internationally.

All of our services are in compliance with cGLP and cGMP requirements. We are FDA registered, AAALAC accredited, DEA licensed and USDA registered, and we have a comprehensive Quality System with a dedicated QA/QC Director to ensure that internal, customer and regulatory requirements are met.

To learn more about our services, request a quote or schedule an audit, please contact us using the form in the lower left, or contact Michael Settles at msettles@tgasciences.com or 781-393-6910 x203.