Benjamin Bronfin, MD
Senior Director of Operations

As Senior Director of Operations, he supervises all areas of site operations including laboratory, facility support, client interaction, and business development at TGA. Dr. Bronfin has over 20 years of experience in RUO and GLP assay development and validation, including PK, PD, and immunogenicity analysis. He has a medical degree from Omsk Medical Academy, Russia, where he then practiced medicine before moving to Boston to pursue research at Beth Israel Deaconess Medical Center (BIDMC), a Harvard affiliated research hospital. Following BIDMC, he worked at Cambridge Biomedical, a bioanalytical CRO, in multiple roles including Director of CRO Services. Dr. Bronfin was responsible for oversight and implementation of assay development, validation and performance in support of clinical trials (pre-clinical through phase IV) and in vitro diagnostic products. He also supervised business development and project life-cycles to ensure compliance with stated IPA requirements, as well as GLP, GCP, and/or CAP/CLIA regulations.

Mike_photo_smallest--183-7300-1Michael R. Settles
Founder, Chief Executive Officer and President

Michael R. Settles, through his leadership and direction, has cultivated the remarkable growth of his Contract R&D Laboratory located just outside of Boston, MA over the past ten years. Initially offering only basic laboratory support in 1996, today TGA Sciences, Inc. offers a fully integrated CRO with GLP/cGMP capabilities, animal studies and FDA compliant clinical trial support available to both national and international markets. A respected member of the CEO Roundtable of Andover, MA, Biotechnology Division, Mr. Settles has more than 20 years of experience working in the Biotechnology sector. Preceding TGA Sciences, Inc., from 1992 to 1998, Mr. Settles was with ImmuLogic Pharmaceutical Corporation serving as an integral part of the Product Development Department for the company’s AllerVax pipeline. From 1989 to 1992, Mr. Settles was employed by T-Cell Diagnostics, Inc. as a Senior Associate Scientist and was involved with the development, validation and product launches of Immunoassay kits. Prior to that, Mr. Settles was employed by the New England Medical Center and Damon Biotech, Inc. serving in various supervisory roles in the Hematology/ Oncology department and manufacturing laboratories, respectively. A New Jersey native, Mr. Settles earned his Bachelor of Science degree from Salem State College in Salem, Massachusetts.

Jill_photo_smallest--183-7297-1Jill E. Settles
Director, Quality Assurance

Ms. Settles directs all quality assurance activities including document management, internal and external auditing, management of quality systems and training of employees. In addition, she coordinates client projects, evaluates project needs, provides consultation, creates standard operating procedures and serves as the IACUC Chairman. Ms. Settles has been with TGA since 1999, beginning in a technical role developing and validating client assays. Prior to coming to TGA, she held R&D positions with Antigenics and Scriptgen Pharmaceuticals, gaining extensive experience in immunoassay development, protein characterization and small molecule screening. Ms. Settles holds a Bachelor of Science degree in Microbiology from the University of Massachusetts at Amherst.

Lisa Greenleaf
Associate Director, Technical Operations

Ms. Greenleaf is responsible for immunoassay development and validation projects (GLP and cGMP), preparing technical reports, data summaries and quantitative analysis. She leads a team of associate scientists developing immunoassays for clients’ requirements and assumes responsibility for projects, which includes client interaction and project organization. Ms. Greenleaf has worked for Scriptgen Pharamceuticals, Inc. and Phylos and holds a Bs.c. in Biochemistry from Northeastern University in Boston, Ma.

Babs_photo_smallest--183-7294-1Babette Haven
Bioassay Group Senior Manager

Ms. Haven is responsible for performing immunoassays, FACS analysis and other immunological analysis. She is instrumental in designing experimental methods for client projects, which also includes presentation of these analysis as well as vast client interaction. She prepares technical reports and data summaries in support of development and validation projects. Ms. Haven was previously employed at Santa Cruz Biotechnology and received her B.A. in Chemistry from the University of California, Santa Barbara.Babette can be reached at

Kate_photo_-_smallest-183-7298-1Kate Patterson

Ms. Patterson is responsible for immunoassay development, validation, and sample analysis under RUO and GxP conditions preparing necessary protocols, technical reports, and data summaries.  She serves as the lead on client projects for technical and scientific aspects of development, validation, and sample analysis through completion of the projects.  She leads a team of research associates to meet the clients’ requirements assuming responsibility for the projects and serving as a point of contact for the study director, project staff, and the client.  Ms. Patterson holds a B.Sc. in Animal Science with a concentration in Pre-Veterinary Medicine from UMASS, Amherst.

Alex Uckermann
In Vivo Assistant Manager

Ms. Uckermann oversees, manages and schedules the animal facility activities; is the main contact for all facility registrations, licenses and procedures (contact person for USDA and AAALAC);.  She previously worked for Charles River Labs for 5 years and attended UCATECI, Dominican Republic. Bunker Hill.

Marissa Recor

Marissa is responsible for the management of G/L, A/R, A/P; preparation of quarterly financial statements; inventory; purchasing and vendors.  She has an MBA in Business Administration and a Masters in Accounting from Bentley College in Waltham, MA.