TGA BioServices offers a variety of bioassays for compound screening, lot release testing in support of GMP manufacturing, determination, of the toxicity of compounds and reagents.

  • Cell Based Assay:
    • Cytokine release assays
    • In-vitro wound healing testing
    • Potency assay
    • Growth factor and interleukin bioassays
    • NAB testing
    • TCID50 and EC50 testing
    • Reporter gene assays
    • Migration and invasion assays
    • ADCC assays
  • Flow Cytometry:
    • Intracellular Cytokine or Tetramer/Dextramer staining
    • T cell functional assays
    • Cytokine production
    • Proliferation and Cytotoxicity
    • Effector/Memory Phenotyping
    • B-cell activation and gene activation (pSTAT)
    • Quantitation of vaccine/antigen-specific cellular immune responses
      Cell signaling pathways, intracellular cytokine & transcription factors
    • Measurement of DNA content, cell death, apoptosis, cell cycle
    • Detection/quantitation/ characterization of T cell responses for Cancer vaccines (CAR T cells)