Apoptosis

Apoptosis studies are some of the many laboratory services TGA Sciences provides to the Pharmaceutical, Biotechnology and Academic communities.

Apoptosis is the term given when programmed cell death (PCD) occurs in multicellular organisms. Apoptosis is one of the main types of programmed cell death which involves a series of biochemical events leading to specific cell morphology characteristics and ultimately death of cells. Characteristic cell morphology of cells undergoing apoptosis include blebbing, changes to the cell membrane such as loss of membrane asymmetry and attachment, cell shrinkage, nuclear fragmentation, chromatin condensation and chromosomal DNA fragmentation. Various methods are employed to investigate apoptosis. These methods include direct measurement of apoptotic cells with flow cytometry and in situ labeling, as well as RNA, DNA, and protein assays that are indicative of apoptotic molecules.